BEETHAM, PETER R.,GOCAL, GREGORY F.W.,SCHOPKE, CHRISTIAN,SAUER, NOEL,PEARCE, JAMES,SEGAMI, ROSA E.,MOZORUK, JERRY
申请号：
CA3014036
公开号：
CA3014036A1
申请日:
2016.09.16
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
Provided herein include methods and compositions for making targeted changes to a DNA sequence. In various aspects and embodiments, methods and compositions for modifying a DNA sequence in a cell (such as a plant, bacterial, yeast, fungal, algal, or mammalian cell) are provided. In some aspects and embodiments the modification of DNA involves combining gene repair oligonucleotides with approaches that enhance the availability of components of the target cell gene repair mechanisms, such as a DNA cutter.
