Jeanne Mary Comstock;Zheng Xin Dong;Michael DeWitt Culler;Yeelana Shen
发明人:
Zheng Xin Dong,Michael DeWitt Culler,Yeelana Shen,Jeanne Mary Comstock
申请号:
US12079885
公开号:
US08258094B2
申请日:
2008.03.28
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention comprises peptidyl analogs according to formulae (I) or (II) as depicted below:(R2R3)-A1-A2-A3-A4-A5-A6-A7-A8-A9-A10-A11-A12-A13-A14-A15-A16-A17-A18-A19-A20-A21-A22-A23-A24-A25-A-26-A27-A28-R1wherein the definitions of A1 to A28 and R1 to R3 are provided for in the specification for each of formulae (I) and (II), pharmaceutically acceptable salts thereof and pharmaceutical compositions comprising an effective amount of a compound of formula (I), that possess agonist or antagonist ghrelin activity, along with therapeutic and non-therapeutic uses thereof.