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Chimeric small molecules for the recruitment of antibodies to cancer cells
专利权人:
YALE UNIVERSITY
发明人:
David Spiegel,Ryan Murelli,Andrew Zhang
申请号:
US14480204
公开号:
US09296708B2
申请日:
2014.09.08
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The compounds according to the present invention comprise an antibody binding terminus (ABT) moiety covalently bonded to a cell binding terminus (CBT) through a linker and optionally, a connector molecule.
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