GREEN, COLIN RICHARD,COUTINHO, FRAZER PAUL,RUPENTHAL, ILVA DANA
申请号:
CA3061738
公开号:
CA3061738A1
申请日:
2018.04.30
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present invention provides novels method of targeting delivery of a compound to hypoxic cells, for example treatment of diseases and disorders associated with hypoxia, comprising administration of a construct comprising a targeting carrier peptide and a compound for delivery to a hypoxic cell. The invention also provides novel methods for the treatment of diseases or disorders of the eye by administration of a novel construct, a nucleic acid encoding a novel construct, and/or a nucleic acid vector comprising a nucleic acid encoding a novel construct. The invention further provides novel constructs, nucleic acids encoding such constructs, and/or nucleic acid vectors comprising nucleic acids encoding such constructs.