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AMINOPYRIMIDINES USEFUL AS INHIBITORS OF PROTEIN KINASES
专利权人:
VERTEX PHARMACEUTICALS INCORPORATED
发明人:
JIMENEZ, JUAN-MIGUEL,COLLIER, PHILIP,MILLER, ANDREW
申请号:
NZ57776807
公开号:
NZ577768A
申请日:
2007.12.19
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed are compounds of formula (I), wherein the substituents are as defined in the specification. The compounds are protein kinase inhibitors particularly useful as GSK-3 inhibitors. The compounds are used in the manufacture of a medicament for treating or lessening the severity of a disease or condition selected from diabetes, Alzheimers disease, Huntingtons disease, Parkinsons disease, AIDS-associated dementia, bipolar disorder, amyotrophic lateral sclerosis (ALS, Lou Gehrigs disease), multiple sclerosis (MS), schizophrenia, leukocytopenia, cardiomyocyte hypertrophy, stroke, and rheumatoid arthritis.
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中国工程科技知识中心
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