Piridopirimidina substituted compounds as inhibitors of FLT3； Pharmaceutical formulation that comprises； and its use for the treatment of hematologic malignancies such as Leukemia, autoimmune diseases and malignant Solid tumors.
KIM HONG WOO,LEE HEE KYU,SONG HO-JUHN,LEE JAEKYOO,KOH JONG SUNG,KIM JUNG-HO,KIM SE WON,LEE IN YONG
申请号：
CL2014002505
公开号：
CL2014002505A1
申请日:
2014.09.22
申请国别(地区):
CL
年份:
2015
代理人:
摘要：
Compounds of Formula (I) and methods for inhibiting kinases, including spleen tyrosine kinases, are disclosed. Also disclosed are methods for treating a kinase-mediated disease or condition by administering to a subject a therapeutically effective amount of the compound of Formula (I).compuestos derivados de fenilamino-piridopirimidina-5-ona, como inhibidores de FLT3； formulación farmacéutica que los comprende； y su uso para el tratamiento de tumores hematológicos malignos tal como leucemias, enfermedades autoinmunes y tumores sólidos malignos
