PROCÉDÉS ET COMPOSITIONS POUR L'ADMINISTRATION AU SNC DE SS-GALACTOCÉRÉBROSIDASE

• 收藏
• 分享

专利权人:

INC.;SHIRE HUMAN GENETIC THERAPIES

发明人:

SALAMAT-MILLER, NAZILA,TAYLOR, KATHERINE,MANNING, KEN,ZHU, GAOZHONG,CAMPOLIETO, PAUL.,SHAHROKH, ZAHRA.,MCCAULEY, THOMAS.,CALIAS, PERICLES.

申请号：

EP11799038

公开号：

EP2588132A4

申请日:

2011.06.25

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

The present invention provides, among other things, compositions and methods for CNS delivery of lysosomal enzymes for effective treatment of lysosomal storage diseases. In some embodiments, the present invention includes a stable formulation for direct CNS intrathecal administration comprising an B-Galactocerebrosidase protein, salt, and a polysorbate surfactant for the treatment of GLD Disease.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/