ECKELMAN, Brendan P.,TIMMER, John C.,DEVERAUX, Quinn
申请号:
EP16740748
公开号:
EP3247407A4
申请日:
2016.01.21
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The invention provides modifications within human or humanized single domain antibody fragments (sdAbs) that prevent recognition by pre-existing antibodies, to isolated polypeptides that include these modifications, and to methods and uses thereof.