Adrian Hayday,Kai Krohn,Annamari Ranki,Part Peterson,Kai Kisand,Edward Stuart,Annalisa MacAgno,Shimobi Onuoha
申请号：
US14369467
公开号：
US09475872B2
申请日:
2013.01.02
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Provided are novel binding molecules of human origin, particularly human antibodies as well as fragments, derivatives and variants thereof that recognize antigens such as native endogenous proteins associated with, e.g., immune response, autoimmune disorders, inflammatory diseases, metabolic disorders, vascular function, neurodegenerative diseases or tumors. More particularly, a human Auto-Immunosome and corresponding monoclonal antibody reservoir are provided. In addition, pharmaceutical compositions, kits and methods for use in diagnosis and therapy of are described.
