CHARLES, Mark,FINLAY, Maurice,NISSINK, Johannes,WOOD, James
申请号：
TN2018000126
公开号：
TN2018000126A1
申请日:
2016.11.30
申请国别(地区):
TN
年份:
2019
代理人:
摘要：
A compound of Formula (I) or a pharmaceutically acceptable salt thereof, where: Q can be 5-methylpyridazin-3-yl, 5- chloropyridazin-3-yl, 6-methylpyridazin-3-yl, or 6-fluoropyridazin-3-yl； R can be hydrogen, fluoro, or methoxy； R<；sup>；1<；/sup>； can be hydrogen, methoxy, difluoromethoxy, or trifluoromethoxy； and R<；sup>；2<；/sup>； can be methyl or ethyl. The compound of formula (1) can inhibit glutaminase, e.g., GLS 1.
