HAMMOND, DAVID J.,LATHROP, JULIA T.,CERVENAKOVA, LARISA,CARBONELL, RUBEN G.
申请号:
CA2507936
公开号:
CA2507936C
申请日:
2003.12.03
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
Ligands that bind to prion proteins and methods for using the ligands fordetecting or removing a prion protein from a sample, such as a biologicalfluid or an environmental sample. The ligands are capable of binding to one ormore forms of prion protein including cellular prion protein (PrPc),infectious prion protein (PrPsc), and recombinant prion protein (PrPr). Prionsfrom various species, including humans and hamsters, are bound by the ligands.Also provided is a method of treating or retarding the development of a prion-associated pathology in a subject.