FRYSZMAN, OLGA M.,LANG, HENGYUAN,LAN, JIONG,CHANG, EDCON,FANG, YUNFENG
申请号:
HK11107635.3
公开号:
HK1149764B
申请日:
2006.08.16
申请国别(地区):
HK
年份:
2012
代理人:
摘要:
Provided are 5-membered heterocycle-based p38 kinase inhibitors. Further provided are pyrazole and imidazole-based p38 kinase, including p38± and p38² kinase, inhibitors. Pharmaceutical composititons coataining the compounds are also provided. Methods of use of the compounds and compositions are also provided, including methods of treatment, prevention, or amelioration of one or more symptoms of p38 Kinase mediated diseases and disorders, including, but not limited to, inflammatory diseases and disorders.