Shugui Yin,Shiqiang Wang,Shaowei Jia,Tao Zhang,Qingzhe Liu
申请号：
US16137546
公开号：
US20200060977A1
申请日:
2018.09.21
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to a technical field of pharmaceutical preparation, in particular to a preparation method of naltrexone implants, including the following steps: (1) dissolving naltrexone and polylactic acid in an organic solvent to form naltrexone microspheres, and drying； (2) placing the naltrexone microspheres in a heated tableting mold for tableting, and obtaining naltrexone implant tablets； (3) dissolving the polylactic acid in the organic solvent to obtain a coating solution, and placing the coating solution in a coating pool, and then immersing the naltrexone implant tablets in the coating solution, and drying in a suspended state.
