您的位置: 首页 > 农业专利 > 详情页

EPITOPES MODIFIES DESTINES A STIMULER LES REPONSES DES LYMPHOCYTES T CD4+
专利权人:
KATHOLIEKE UNIVERSITEIT LEUVEN;LIFE SCIENCES RESEARCH PARTNERS VZW
发明人:
SAINT-REMY, JEAN-MARIE
申请号:
CA2863126
公开号:
CA2863126A1
申请日:
2013.01.30
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The present invention relates to immunogenic peptides comprising a T-cell epitope. Said peptides are modified such that CD4+ T-cell responses are obtainable that are much stronger than the CD4+ T-cell responses obtained with the same peptides not comprising said modification. In particular, the modification is the addition of a cysteine, insertion of a cysteine or mutation into a cysteine of a residue at a position adjacent to but outside the MHC-binding site of the peptide. Further disclosed are the use of such modified peptides in treating, suppressing or preventing diseases such as infectious or allergic diseases and autoimmune diseases, in preventing or suppressing graft rejection, or in the eradication of tumor cells.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充