The invention provides an analysis method of ultrasound echo signals based on statistics of scatterer distributions. The beginning of steps, choosing an ultrasound echo signal as a center, and calculating the signal image values of all ultrasound echo signals within a window block in an ultrasound image data to obtain an ultrasound scatterer value. Then, choosing another ultrasound echo signal as the center to repeat the previous steps until all of ultrasound echo signals may be calculated. The interval between each of ultrasound echo signal is one point distance. Finally, to output an ultrasound scatterer mode image with all ultrasound scatterer values by utilizing color scale. The ultrasound scatterer mode image can assist doctor to confirm the relative region of lesion in a target organ.