Enteric coated multiparticulate formulations that use L menthol as an active ingredient are disclosed. In one embodiment the multiparticulate formulation comprises a plurality of particulates having a reduced release under gastric conditions and an elevated release at neutral pH. The particulates comprise a core comprising L menthol as an active ingredient. The L menthol is supplied to the core as an at least 80% pure L menthol material. An enteric coating is over the core. The enteric coating is effective to release at least about 80% of the L menthol within about two hours of being placed in a substantially neutral pH environment. Other aspects of the invention include methods of making and methods of using the multiparticulate formulations.
