FRANCIS, RAYMOND JOSEPH,BARDIN, DAVID,HUNT, GREGORY LEE,TAURIAINEN, ANTTI JUHANI,VALKAMA, MARKKU JUHA KALERVO,LIEDERT, RALPH,TUOMINEN, JARKKO TAPANI
申请号:
CA3039258
公开号:
CA3039258A1
申请日:
2018.05.17
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
A method for manufacturing microneedle devices and systems and tools for implementing same. The method can include manufacturing a replica mold and forming a microneedle array via the replica mold. The replica mold can be manufactured by disposing replica mold material on a master mold and curing the replica mold material. To reduce manufacturing time, the replica mold material preferably is cured at a high temperature for a relatively short time and then cooled quickly before removal from the master mold. The microneedle array can be formed by disposing microneedle material on the replica mold under vacuum and drying the microneedle material in single or successive disposing and drying operations. One or more optional backing layers can be added to the microneedle array when forming the microneedle device. Advantageously, the disclosed methods, systems and tools can be used to manufacture skin-applied patches for delivering cosmetic and therapeutic agents.