The present disclosure provides a brush polymer, including: a linear polymer main chain and brush structural side chains, including: a hydrophobic molecular branch, and a hydrophilic molecular branch and/or an anti-biofilm /or an anti-microbial molecular branch, wherein the linear polymer main chain is coupled to the side chains by covalent bonds formed between a hydroxyl group and a reactive functional group, wherein the reactive functional group includes: isocyanate, carboxyl, or epoxy. The present disclosure also provides a medical use of the brush polymer.本發明提供一種梳狀結構高分子,包括:線性高分子主鏈;以及梳狀側鏈結構,包括:疏水性分子鏈段;以及親水性分子鏈段及/或抑制生物膜/或抗菌之分子鏈段,其中該線性高分子主鏈係以羥基與該梳狀側鏈結構之反應性官能基形成共價鍵結相互連接,其中該反應性官能基包括:異氰酸酯、羧基、或環氧基。本發明亦提供上述梳狀結構高分子的醫療應用。11...線性高分子主鏈12...疏水性分子鏈段13...親水性分子鏈段14...抑制生物膜/或抗菌之分子鏈段
