A mouthguard includes lateral cheek compaction domes which compressibly fill the space between the inside of the cheek and the rear teeth when worn. The domes are ellipsoid in shape and provide elasticity which allows the muscles of the cheek to comfortably grip the mouthguard. The internal aspects of the cheek compress the domes against the outer tooth and gum surfaces to hold the mouthguard in place even when the teeth are not biting on the bite plate section. This holds the mouthguard in place as the jaws move when speaking or during deep breathing.