Yang LIU,Yin WANG,Yan LIU,Christopher BAILEY,Pan ZHENG
申请号：
US15774217
公开号：
US20180344642A1
申请日:
2016.11.09
申请国别(地区):
US
年份:
2018
代理人:
摘要：
A liposomal drug formulation for treating a disease in a patient characterized by overexpression of HIF-1α and/or HIF-2α includes a plurality of liposomes in a pharmaceutically acceptable carrier. The liposomes encapsulate echinomycin and are made from a peglyated phospholipid, a neutral phosphoglyceride, and a sterol. The PEGylated liposomes may be used to treat proliferative diseases, leukemia, cancer, autoimmune diseases and graft-versus-host disease.
