A medical observation system includes: a microscope； a support including a first joint configured to hold the microscope such that the microscope is rotatable about a first axis parallel to an optical axis of the microscope； and a first arm configured to hold the first joint and extend in a direction different from a direction of the optical axis of the microscope； a light guide cable inserted in the support and configured to guide illumination light to the microscope； and a binder configured to bind the light guide cable, wherein at least a part of the light guide cable is arranged along the first axis in a first section, the light guide cable extends in a direction different from the first axis in a second section, and the binder is configured to bind the light guide cable in the second section.
