Preparation of a dental prosthesis that includes a gingiva part having retention holes for seating of manufactured teeth, with the retention holes being enlarged relative to the manufactured teeth. Wax in the enlarged retention holes permits adjustments in positioning of the manufactured teeth, and a helper structure preserves this positioning when the wax is removed and a curable gingiva material is filled into the retention holes. Aspects described herein include digital and/or automatic design of the dental prosthesis and its constituent pieces, as well as automated fabrication thereof in whole or in part, such as in a dental CAD/CAM system.