The invention relates to a sensor device for in vivo monitoring of glucose in diabetics, wherein the sensor device comprises a micro-array with multiple sensors to be implanted subcutaneously in a patient wherein each sensor may be activated separately for monitoring purposes. Preferably, the sensors in said micro-array are comprised in a mold that is covered by a metal membrane, and even more preferably, the membrane is electrically openable to expose each specific activated sensor in the micro-array separately for monitoring purposes. A transceiver may be provided for monitoring signals obtained by each specific activated sensor to an external receiver and the receiver may be connected to a display means for displaying data representative of the signals obtained by the specific activated sensor.