NATHALIE GARCON,Moncef Mohamed Slaoui,Christian Van Hoecke
申请号：
US14307729
公开号：
US20140302090A1
申请日:
2014.06.18
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The invention relates to the use of an influenza antigen preparation obtainable by the following process, in the manufacture of an intradermal flu vaccine:(i) harvesting of virus-containing material from a culture(ii) clarification of the harvested material to remove non-virus material(iii) concentration of the harvested virus(iv) a further step to separate whole virus from non-virus material(v) splitting of the whole virus using a suitable splitting agent in a density gradient centrifugation step(vi) filtration to remove undesired materialswherein the steps are performed in that order but not necessarily consecutively.
