CHANCELLOR, MICHAEL B.,JANKOWSKI, RONALD,PRUCHNIC, RYAN,HUARD, JOHNNY
申请号：
CA2674795
公开号：
CA2674795C
申请日:
2008.01.11
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The present invention provides muscle-derived progenitor cells that show long-term survival following transplantation into body tissues and which can augment soft tissue following introduction (e.g. via injection, transplantation, or implantation) into a site of soft tissue. Also provided are methods of isolating muscle-derived progenitor cells, and methods of genetically modifying the cells for gene transfer therapy. The invention further provides methods of using compositions comprising muscle-derived progenitor cells for the augmentation and bulking of mammalian, including human, soft tissues in the treatment of various functional conditions, including malformation, injury, weakness, disease, or dysfunction. In particular, the present invention provides treatments and amelioration for urinary incontinence and other urinary tract pathologies.
