The present invention provides a multi-target vital sign detection system, which comprises a transmitter, a receiver and a processor. The transmitter is configured to transmit a millimeter wave signal to a detection area, and the receiver is configured to receive a reflected millimeter wave signal reflected by a plurality of target reflections. The processor executes: analyzing the reflected millimeter wave signal to generate the signal strength versus distance data; performing a maximum holding process to generate signal extreme value-distance data; performing a peak search algorithm to generate a peak list including a plurality of peak values and a plurality of corresponding peak distances; generating an array of distances including a plurality of distance variables; perform a vital sign detection algorithm to generate multiple sets of vital sign data.本發明公開一種多目標生命徵象偵測系統,其包括傳送器、接收器及處理器。傳送器用於向偵測區域傳送毫米波訊號,接收器用於接收由多個目標反射產生的反射毫米波訊號。處理器執行:分析反射毫米波訊號產生訊號強度對距離資料;進行保留極值處理,產生訊號極值對距離資料;執行峰值搜尋演算法取得峰值列表,包括多個峰值及多個對應的峰值距離;產生包括多個距離變數的距離陣列;執行生命徵象偵測演算法,以產生多個生命徵象資料。