Bone reconstruction implants and systems comprising the implants are provided. The implants and systems find use in monitoring and/or modulating the health of a patient. The bone reconstruction implants may be contoured to conform to the surface contours of a bony defect and comprise one or more functional elements. The functional elements may be positioned within the bone reconstruction implant so as to maximize alignment or interaction with functional elements in implanted medical devices, internal anatomical features or external devices.
