Compounds for the treatment of human immunodeficiency virus (HIV) infection are disclosed. The compound has the following formula (I): including its stereoisomers and medicinal salts, wherein R1, x, W, Y1, Y2, Z1 and Z4 are as defined herein. Methods related to the preparation and use of such compounds and pharmaceutical compositions containing such compounds are also disclosed.公開了用於治療人類免疫缺陷性病毒(HIV)感染的化合物。所述化合物具有下式(I):包括其立體異構體及可藥用鹽,其中R1、X、W、Y1、Y2、Z1和Z4為如本文定義的。還公開了與這樣的化合物以及包含這樣的化合物的藥物組合物的製備和用途有關的方法。