A process for the preparation of E-farnesyl acetone characterized by reaction of nerolidol with isopropenylmethyl ether in the presence of an acidic catalyst at elevated temperature and isolation by fractionated distillation.高温での酸性触媒の存在下におけるネロリドールとイソプロペニルメチルエーテルとの反応、および分画蒸留による単離を特徴とするE-ファルネシルアセトンの調製方法。