PROBLEM TO BE SOLVED: To provide a novel means to induce disease resistance in gramineous plant.SOLUTION: The effective component of an agent to induce disease resistance in gramineous plants of the invention is a polypeptide comprising part of an elongation factor EF-Tu and including specified amino acid sequences and consisting of not more than 200 amino acid residues and having an activity to induce immune response in gramineous plants, for example, a polypeptide having an amino acid sequence corresponding to the amino acid sequence at positions 176-225 of a certain amino acid sequence or a variant thereof having substitution, deletion, insertion or addition of one or several amino acid residues at the positions 176-225 and having an activity to elicit immune response in gramineous plants.COPYRIGHT: (C)2015,JPO&INPIT【課題】イネ科植物の病害抵抗性を誘導する新規な手段を提供する。【解決手段】伸長因子EF-Tuの一部からなり、特定のアミノ酸配列を含み、かつ、200個以下のアミノ酸残基からなるポリペプチドであって、イネ科植物の免疫応答を誘導する活性を有するポリペプチド、例えば下記のポリペプチドを、イネ科植物の病害抵抗性誘導剤の有効成分とする:(c)他の特定のアミノ酸配列の内の176~225位のアミノ酸配列を有するポリペプチド、(d)他の特定のアミノ酸配列の内の176~225位のアミノ酸配列において、1若しくは数個のアミノ酸残基の置換、欠失、挿入、または付加を含むアミノ酸配列を有し、かつ、イネ科植物の免疫応答を誘導する活性を有するポリペプチド。【選択図】図3