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专利权人:
INCYTE CORPORATION
发明人:
PARIKH, BHAVNISH,SHAH, BHAVESH,YELESWARAM, KRISHNASWAMY
申请号:
PE2012002197
公开号:
PE20130216A1
申请日:
2011.05.20
申请国别(地区):
PE
年份:
2013
代理人:
摘要:
It refers to a kind of effective formula, including: (a) oil emulsion in water, containing 35% to 65% water by formula weight, and two oil-containing components, such as Vaseline, fatty alcohol, mineral oil, etc., containing 10% to 40% water by formula weight, (3) an emulsified component, such as glycerides and sorbitans, containing 1-9% by weight of the formula; and (b) a therapeutic agent, such as (R) - 3-cyclopentyl-3 - [4 - (7h pirrolo [2, 3-d] pirimidin-4-il) - 1h-pirazol-1-il] acetone, Calculated by the formula of free radical with the weight of 0.5% to 1.5%;In addition, it also includes a stabilizer, such as polyurethane, with a content of 0.05% to 5% by formula weight, a solvent component, such as asphalt and multi tar glycerin, with a content of 10% to 35% by formula weight, and an anti microbial preservative component, such as Arabian asphalt and phenylethanol, with a content of 10% to 35%. Formula weight from 0.05% to 3% plus a coagulant such as edoto sodium This formula is useful for the treatment of skin diseases such as dermatitis or cortitis.SE REFIERE A UNA FORMULACION FARMACEUTICA QUE COMPRENDE: A) UNA EMULSION DE ACEITE EN AGUA, QUE COMPRENDE: i) AGUA, EN UNA CANTIDAD DE 35% A 65 % EN PESO DE LA FORMULACION, ii) UN COMPONENTE OLEOSO TAL COMO, VASELINAS, ALCOHOLES GRASOS, ACEITES MINERALES, ENTRE OTROS, EN UNA CANTIDAD DE 10% A 40 % EN PESO DE LA FORMULACION, Y iii) UN COMPONENTE EMULSIONANTE TAL COMO ESTERES GRASOS DE GLICERILO Y ESTERES GRASOS DE SORBITAN, EN UNA CANTIDAD DE 1% A 9 % EN PESO DE LA FORMULACION; Y B) UN AGENTE TERAPEUTICO TAL COMO (R)-3-CICLOPENTIL-3-[4-(7H-PIRROLO[2,3-d]PIRIMIDIN-4-IL)-1H-PIRAZOL-1-IL]PROPANONITRILO, EN UNA CANTIDAD DE 0.5% A 1.5 % EN PESO DE LA FORMULACION CON RESPECTO A LA BASE LIBRE; ADEMAS COMPRENDE UN AGENTE ESTABILIZANTE TAL COMO POLISACARIDOS, EN UNA CANTIDAD DE 0.05% A 5 % EN PESO DE LA FORMULACION, UN COMPONENTE SOLVENTE TAL COMO ALQUILENGLICOLES Y POLIALQUILENGLICOLES EN UNA CANTIDAD DE 10% A 35 % EN PESO
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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