PAYNE, JOSEPH E.,CHIVUKULA, PADMANABH,TANIS, STEVEN P.
申请号:
CA2993350
公开号:
CA2993350A1
申请日:
2016.07.29
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Described herein is a compound having the structure of formula I, II, or III, wherein R comprises a double stranded RNA molecule, and L1 L2, and L3 independently for each occurrence comprise a ligand selected from the group consisting of a carbohydrate, a cholesteryl, or a peptide; a pharmaceutically accepted salt or pharmaceutical composition thereof; and a method of making the compound.