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Fluorescent probe for detecting dipeptidyl peptidase IV
专利权人:
The University of Tokyo
发明人:
Yasuteru Urano,Yasuyuki Seto,Haruna Onoyama,Yugo Kuriki,Mako Kamiya
申请号:
US15324147
公开号:
US10383956B2
申请日:
2015.07.10
申请国别(地区):
US
年份:
2019
代理人:
摘要:
[Problem] To provide a novel fluorescent probe for dipeptidyl peptidase IV, and a detection method and a detection kit using the fluorescent probe.[Solution] A fluorescent probe for detecting dipeptidyl peptidase IV (DPP-IV), said probe comprising a compound represented by formula (I) or a salt thereof. In formula (I): A and B are either the same or different and independently represent an amino acid residue, provided that A is bonded via an amide bond to NH in an adjacent formula and B is bonded via an amide bond to A; R1 represents hydrogen atom(s) or 1 to 4 substituents bonded to the benzene ring, said substituents being either the same or different; R2, R3, R4, R5, R6 and R7 independently represent a hydrogen atom, a hydroxyl group, an alkyl group or a halogen atom; R8 and R9 independently represent a hydrogen atom or an alkyl group; and X represents a C1-C3 alkylene group.
来源网站:
中国工程科技知识中心
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