2-DISUBSTITUTED SUBSTITUTED NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF FOR TREATMENT OF VIRAL DISEASES

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专利权人:

MERCK SHARP & DOHME CORP.

发明人:

GIRIJAVALLABHAN, VINAY,BOGEN, STEPHANE,PAN, WEIDONG,DANG, QUN,DAVIES, IAN

申请号：

EP13847502

公开号：

EP2909210A4

申请日:

2013.10.11

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

2&prime-disubstituted substituted nucleoside derivatives of formula (I) and pharmaceutically acceptable salts thereof are disclosed: (1), wherein A is N3 or NH2 and X, Y, R1, R2, R3, R4, R5 and R18 are as defined herein. Compositions comprising at least one 2&prime-disubstituted nucleoside derivative, and methods of using the 2&prime-disubstituted nucleoside derivatives for treating or preventing HCV infection in a patient are disclosed.

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