Paul S. FRENETTE,Sandra PINHO,Qiaozhi WEI,Sung Kyun LEE
申请号:
US16773907
公开号:
US20200270349A1
申请日:
2020.01.27
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Antibodies and antibody fragments that inhibit the activity of vascular cell adhesion molecule 1 (VCAM1) and/or macrophage erythroblast attacher (MAEA) are provided, along with formulations and kits comprising these antibodies and antibody fragments and the use of the disclosed compositions, formulations, and kits to treat cancers, sickle cell disease, and Polycythemia Vera.