A scalpel handle (10,210) includes an outer body (12,212) defining a first end (20,220) and a cavity (24,224) therein and an insert (22,222) defining a blade holder (44,244) disposed at a first end thereof and positionable within the cavity of the outer body with the blade holder extending outwardly away from the first end of the outer portion. A shield (30,230) is coupled with the body and positionable around the blade holder, and a removal wedge (36,236) fixed with respect to the shield and disposed in a substantially fixed lateral position at least partially aligned with a portion of the blade holder.