Chris LU,Shou-Ih HU,Michaela KNEISSEL,Christine HALLEUX
申请号：
US13225966
公开号：
US20120003219A1
申请日:
2011.09.06
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to the use of modulators of the sclerostin:sclerostin-binding-partner interaction for the treatment, amelioration, and diagnosis of sclerostin-related disorders, e.g., osteoporosis and sclerosteosis, and sclerostin-related disorders, e.g., cancers and cardiovascular disorders. The invention also relates to the use of sclerostin-binding-partner mimetics for the treatment, amelioration, and diagnosis of sclerostin-related disorders. Assays for the identification of modulators of the sclerostin:sclerostin-binding-partner interaction, as well as the resulting signaling, are also provided.
