It can maintain a soft feel and rapid expansion of the application site of dermal fillers may be used alone as a main component a dextran cross-linked molecular weight of 100,000 or less in 30,000, the present invention is the before treatment since there is no need to pre-treatment such as allergic reaction test, the cost is cheap, easily decomposed in the body, is not absorbed, it can be maintained stably for a long time even more volume expansion effect of the treatment, the skin filling of a large amount of 20cc or more It is perfectly suited for use in treatment, such as injection penis enlargement that requires the injection of the agent, the manufacturing process is more simple, there is a further facilitate effective commercialization, feel is soft at the time of injection to the bottom of the skin, new dermal filler composition which can be used on the skin of a wide range of other parts of the body, including the face, not only the skin of the penis and a manufacturing method thereof. [Selection] Figure Figure 1本発明は、分子量が30、000以上の100、000以下である架橋されたデキストランを主成分として単独で用いても皮膚充填剤の適用部位の迅速な拡大と軟らかい触感を維持でき、施術前にアレルギー反応検査などの前処置が必要なく、費用が安くて、体内で容易に分解、吸収されないため、施術による体積拡大効果をより一層長期間安定的に維持できて、20cc以上の多量の皮膚充填剤の注入を必要とする注射陰茎拡大のような施術でも使用に適しており、製造工程がより単純で、実用化がさらに容易な効果があり、皮膚の下への注入時に感触が軟らかくて、陰茎の皮膚だけでなく顔面を含む人体の他の広範囲な部位の皮膚にも使用が可能な新しい皮膚充填剤組成物およびその製造方法に関する。【選択図】図1
