MONTES, MARTIN,LOUGHMAN, THOMAS CIARAN,ROUME, CHANTAL,CHERIF-CHEIKH, ROLAND
申请号:
CA2786181
公开号:
CA2786181C
申请日:
2011.01.11
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The invention relates to a process for the preparation of injectable pharmaceutical compositions for the sustained release of somatostatin analogues and to pharmaceutical compositions prepared according to the process. In a preferred aspect the process comprises the steps of combining lanreotide acetate and acetic acid, lyophilizing the resulting mixture only once, and hydrating the lyophilizate. Acetic acid may be added to a desired pH during the final step of the process.