Jaeki Min,Pahk Thepchatri,Yuhong Du,Dennis C. Liotta,Haian Fu
申请号:
US13122798
公开号:
US20120022070A1
申请日:
2009.10.06
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Novel classes of molecular chaperone Heat shock protein 90 (Hsp90) inhibitors are disclosed. These compounds are useful in treating and preventing cancer and other Hsp90-related diseases and conditions, such as inflammation and neurodegenerative disorders. Methods of treating and preventing cancer and other Hsp90 related diseases and conditions are disclosed that include administering to the subject a therapeutically effective amount of an Hsp90 inhibitor. Methods of preparing the novel Hsp90 inhibitors are also provided.