OKKLO LIFE SCIENCES B.V.;STICHTING SANQUIN BLOEDVOORZIENING
发明人:
MEIJERS, JOSEPHUS CORNELIS MARIA,BAKHTIARI, KAMRAN,PETERS, STEPHAN LEONARD MARIA,ZOLLINGER, DANIEL PHILIPP
申请号:
CA3022455
公开号:
CA3022455A1
申请日:
2017.05.01
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The invention relates to substituted cyclodextrins comprising at least one substituent -S-(Cn-alkylene)-R and pharmaceutically acceptable salts thereof, pharmaceutical compositions, kits of parts and their use as procoagulants. The invention further relates to said cyclodextrins for use in methods of reversing an anticoagulant effect of an anticoagulant in a subject, in methods for reducing or preventing bleeding in a subject and in methods for the treatment or prevention of a blood coagulation disorder.