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ИНГИБИРОВАНИЕ ПРОТЕАЗЫ NS3-NS4 ВИРУСА HCV
专利权人:
ВЕРТЕКС ФАРМАСЬЮТИКАЛЗ ИНКОРПОРЕЙТЕД (US)
发明人:
ЛИНЬ Чао (US),ТЭЙЛОР Уилльям П. (US)
申请号:
RU2010135497/15
公开号:
RU2010135497A
申请日:
2010.08.24
申请国别(地区):
RU
年份:
2012
代理人:
摘要:
The present invention relates to inhibiting the activity of non-genotype 1 hepatitis C virus (HCV) NS3-NS4A protease activity. More particularly, the invention relates to inhibiting the activity of the protease from HCV genotype-2 or HCV genotype-3. The methods of the invention emply inhibitors that act by interfering with the life cycle of the HCV and are also useful as antiviral agents. The invention further relates to compositions comprising such compounds either for ex vivo use or for administration to a patient suffering from genotype-2 or genotype-3 HCV infection. The invention also relates to methods of treating an HCV infection in a patient by administering a composition comprising a compound of this invention.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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