Jianguo Cao;Jeffrey P. Whitten;Gonul Velicelebi;Jonathan Grey;Kenneth A. Stauderman;Evan Rogers;Brian Dyck;Zhijun Wang;Yazhong Pei
发明人:
Gonul Velicelebi,Kenneth A. Stauderman,Jeffrey P. Whitten,Yazhong Pei,Jianguo Cao,Zhijun Wang,Evan Rogers,Brian Dyck,Jonathan Grey
申请号:
US13050724
公开号:
US08383670B2
申请日:
2011.03.17
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Described herein are compounds of Formula (I):wherein A, J, Z, X, R1, and R4 are defined herein, and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.