CHANG, LI CHIEN,张立乾,張立乾,YANG, CHI YU,杨启裕,楊啟裕,LIN, YI JUAIN,林宜娟,林宜娟
申请号：
TW099101846
公开号：
TWI516275B
申请日:
2010.01.22
申请国别(地区):
TW
年份:
2016
代理人:
摘要：
The present invention provides a pharmaceutical preparation in powder-like form comprising a therapeutically effective amount of human Factor IX (hFIX) encapsulated by a lipophilic biodegradable polymer or copolymer to form a microsphere, whereby the pharmaceutical preparation provides a sustained release of hFIX and a prolonged biological activity.本發明提供一種粉末狀醫藥劑型,其包含治療有效量之人類第九凝血因子(hFIX),其被親脂性生物可分解聚合物或共聚物包覆而形成微小球,因而使該醫藥劑型提供緩釋hFIX及延長生物活性的功效。
