KYM PHILIP R,WANG XUEQING,SEARLE XENIA B,LIU BO,YEUNG MING C,ALTENBACH ROBERT J,VOIGHT ERIC,BOGDAN ANDREW,KOENIG JOHN R
申请号：
IN201717015365
公开号：
IN201717015365A
申请日:
2017.05.01
申请国别(地区):
IN
年份:
2017
代理人:
摘要：
The invention provides for compounds of formula (I), wherein R1, X, Y, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, m, and R have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions mediated and modulated by CFTR, including cystic fibrosis, Sjgrens syndrome, pancreatic insufficiency, chronic obstructive lung disease, and chronic obstructive airway disease. Also provided are pharmaceutical compositions comprised of one or more compounds of formula (I).
