Rosalind Franklin University of Medicine and Science
发明人:
申请号：
EP06786414.0
公开号：
EP1904085B1
申请日:
2006.06.30
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
The present invention relates generally to the use of &gamma；-glutamyl antioxidants, particularly &gamma；-glutamyl-cysteine, as cytoprotective agents to prevent reperfusion injury (i.e., hemorrhagic transformation) of the blood-brain barrier during reperfusion following an ischemic stroke. The &gamma；-glutamyl antioxidants can be used alone or used in combination with an agent which inhibits the reverse movement of Na/Ca exchange in the blood-brain barrier such as 2-[2-[4-(4-nitrobenzyloxy)phenyl]ethyl]isothiourea methanesulphonate (KB-R7943).
