Paul W. Sternberg;Suk Hen Chow;Daniel A. Lee;David A. Prober
发明人:
Suk Hen Chow,Daniel A. Lee,David A. Prober,Paul W. Sternberg
申请号:
US14618523
公开号:
US20150246140A1
申请日:
2015.02.10
申请国别(地区):
US
年份:
2015
代理人:
摘要:
In some aspects, the invention relates to methods of treating conditions associated with sleep disorders, comprising administering an agent that modulates the activity of a neuropeptide receptor or a neuropeptide receptor ligand. In some aspects, the invention relates to methods of screening agents that modulate the activity of a neuropeptide receptor in an organism, optionally using cells or organisms comprising a genetic modification that affects a neuropeptide signaling pathway. In some aspects, the invention relates to methods of characterizing a condition associated with a sleep disorder comprising sequencing a nucleic acid encoding either a neuropeptide receptor or a neuropeptide receptor ligand and comparing the sequence with a reference sequence.