Fabre, Virginie,Rocca, Celine,Riffard, Pierre,Calvosa, Eric
申请号:
AU2010233602
公开号:
AU2010233602B2
申请日:
2010.04.08
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
The subject matter of the invention is a method for purifying the rabies virus, comprising a single step of ion exchange chromatography, said step being a cation exchange chromatography according to which: a) the supernatant of a culture of cells infected with this virus is brought into contact with a cation exchange chromatography substrate comprising a matrix of polymethacrylate onto which sulphoisobutyl groups have been grafted such that the rabies virus binds to this substrate, and b) the virus is eluted from the substrate thereof.