Anan Chuntharapai,Gregory D. Plowman,Marc Tessier-Lavigne,Yan Wu,Weilan Ye
申请号：
US13708761
公开号：
US20140004038A1
申请日:
2012.12.07
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to the use of VEGF antagonists and alpha5beta1 antagonists for treating cancer and inhibiting angiogenesis and/or vascular permeability, including inhibiting abnormal angiogenesis in diseases. The present invention also relates to use of a VEGFR agonists and alpha5beta1 agonists to promote angiogenesis and vascular permeability. The present invention also relates to new anti-alpha5beta1 antibodies, compositions and kits comprising them and methods of making and using them.
