Wening, Klaus,Wening, Klaus,Barnscheid, Lutz,Barnscheid, Lutz,Schwier, Sebastian,Schwier, Sebastian
申请号:
HRP20181716
公开号:
HRP20181716T1
申请日:
2018.10.19
申请国别(地区):
HR
年份:
2018
代理人:
摘要:
A tamper-resistant pharmaceutical dosage form comprising a pharmacologically active ingredient embedded in a prolonged release matrix, which comprises a prolonged release matrix material selected from the group consisting of nonionic acrylic polymers and waxy materials and which provides prolonged release of the pharmacologically active ingredient, resistance against solvent extraction, resistance against grinding, and resistance against dose-dumping in aqueous ethanol.